The
duration of the Intensity Modulated
Radiation Therapy was long, and I embarked on it with no guarantees, but from
the start I have expected the best. And so far, I am getting a good outcome.
Only problem: It’s far from over.
It
is more than a month since I completed my 45th IMRT session. What’s
called for now? Another color Doppler ultrasound by Duke Bahn, MD, will show
how much the cancer is diminished. Add another PSA and that should be the
completion of IMRT.
I
admit that I am getting kind of excited. Still, it is part of my
self-protection policy not to expect
miracles. The truth is, Dr. Chaiken never made any promises regarding a number
of my concerns: What can I make of the shrinking PSA readings? What can I
expect regarding tumor size? Do I dare think in terms of a “cure?”
And
what about blood flow feeding the cancer cells? We have Bahn’s color Doppler
results going back almost two decades. The last set of images showed massive
blood flow to the tumors. So my first step will be to start with the Duke.
The
drive to Dr. Bahn’s office in Ventura seems longer than ever. Finally, we get
to Brent Street, to the Prostate Institute of America. We get started right away and I am, butt-hole
lubricated to receive the ultrasound probe while lying on my left side, facing
the Duke’s ultrasound screen.
Both
Jeanne and he are seated behind me. And there on the screen are the color Doppler
pictures revealing the status of Blum’s prostate: the dark shadow which is the
tumor, and most telling, the red threads indicating blood flow to the tumor—the
cancer’s lifeline and nutrient source.
As
always, Dr. Bahn is very quiet and meticulous, taking what seems to me like a
long time to analyze the images. Jeanne asks about the seminal vesicle, and
Duke replies, “It’s not an issue anymore.” He doesn’t explain; we don’t ask. Mostly
I keep my eyes closed, but when I open them I catch small adjustments on the
screen. It seems to take forever. Then, out slides the probe. He says, “We’re
done,” and scurries off to his office while I wipe away the jelly and dress,
wondering: Will this be my last color
Doppler ultrasound?
The
Duke does his write-up, and then shows me the last color Doppler. Although he
tends to be mild-mannered and unexcitable, I catch a thread of—what? Enthusiasm,
perhaps, in his voice? He seems pleased with the results.
“Over 80 percent, gone. What we call
apoptosis,” he explains, “apoptosis being cell death.” Jesu! I’ve known about
apoptosis for years!
Then
the Duke tells me something I did not know and am not happy to hear: That there
is no immediate result. That the out-working of apoptosis [the IMRT effect]
will stretch out, continuing for a number of months into the future, often as
much as a year,
What
about continuing Avodart? I have a feeling that I should. And the Duke says,
yes, absolutely continue. Why? Important to retard transition of testosterone
into dihydrotestoseterone. And, Important to monitor inflammation to keep it down. So for once,
it's a situation where PSA really does count.
Back home, Jeanne is totally exited when she
tells me, “The reduction in blood flow was amazing. The right side of the last color Doppler image was a rat’s
nest of blood flow—so many blood vessels, all criss-crossing and jammed
together. And now that entire side showed only a trace of red here and there.
The difference was incredible!”
Still,
we need a final PSA reading. If it follows pattern, it should now be well under
five.
Two
days later I received the Duke’s summary: The volume of the tumors was dramatically
reduced: Before treatment, the right lobe tumor was 22 x 17 mm; after treatment
it was down to 14 x 11 mm. The shadowy area on the left lobe which was 27 x
23 mm before treatment, had shrunk to 15 x 13 mm. [The lesions were also markedly
reduced in size.] Pretty dramatic results, I thought, from such non-invasive
treatment.
Here’s
how the Duke summed up his test findings: “A significant decline of tumor
volume involving both the right and left lobes. Significant reduction of micovascular density (Now 1+
grade, where it was 3+ before) . Reduced
tumor neovascularity .(Another way of saying the same thing). . . Significantly
declining trend of his PSA . . .”
But
then the Duke knocked the wind out of me with this: “I clearly told Mr. Blum
that we may not see a full radiation effect soon after finishing the treatment.
It may take months, if not a year.” Then he advised monitoring my PSA, adding,
“It will be satisfactory if his PSA nadir reaches 1.0 or under.”
So
it’s far from over! I suppose I had half-expected the damn cancer to shrivel up
and disappear. Hardest to accept was the fact that I will probably not know how
effective the IMRT has been for an entire
year, maybe longer. What I do
know for damn sure is that I can’t get additional IMRT. Not to the same tissue.
The tissue targeted has received its maximum tolerable lifetime dose.
So
what to do? Eat good food. Continue with Avodart. Get regular exercise. Avoid sugar and anger
since according to Traditional Oriental Medicine, cancer is an angry disease. And
anger and sugar feed cancer.
Then
this disappointment: Turns out my PSA hasn’t budged. It’s still at 9.5 where it
was six weeks ago. And it didn’t reassure me to learn that the Duke doesn’t
want to see me for at least six months. A year of living with uncertainty. With
the jury still out.
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