BY MARK SCHOLZ, MD
As we get older, we run into all
kinds of difficulties. Poor hearing, sexual dysfunction, memory problems
and arthritic joints, just to name a few. Bladder issues in particular can be
troublesome, interrupting sleep, making us dread long drives or forcing us to
visit the bathroom at an inopportune time.
As a prostate oncologist taking care of many men who are in their
60s and 70s, it’s no surprise that I hear a lot about urinary difficulties. These problems are often thought to result from prostate
enlargement, otherwise known as BPH. The swollen gland ends up pinching the
urinary passage way (called the urethra). Slow urination and incomplete
emptying of the bladder are the result.
Prostate gland enlargement with
incomplete bladder emptying can frequently be solved with common prescription
medications like Flomax, Rapaflo and Uroxatrol which relax the muscles in the
wall of the urethra and help to open up the passageway. Proscar and
Avodart can shrink the prostate but they also tend to shrink your libido. The
most popular treatment is a nonprescription—Saw Palmetto an herbal product
that works by relaxing the muscles in the urethra.
However, after doing thousands of color Doppler ultrasound
examinations, which by the way is the most precise way to measure the size of
the prostate, I have learned that BPH is a less common cause of men’s urinary
problems. So what is the primary reason for men’s urinary frustrations?
Prostatitis—low grade inflammation of the gland with secondary irritation.
What causes prostatitis? In a minority of cases it is due to bacterial
infection. When this type of prostatitis occurs it may improve with
antibiotics. But for the vast majority of cases we simply don’t know the
cause. Virus or autoimmune causes have been theorized but nothing has
been proven. Our ignorance, however, has nothing to do with its prevalence. It
is not widely realized, but almost all men have
some degree of chronic inflammation in their prostate glands.
Though we don’t know the precise etiology, anti-inflammatory
medications can be quite effective at alleviating the symptoms of prostatitis.
Over the counter products like Aleve and Motrin are effective. Celebrex, is a
prescription anti-inflammatory agent that is billed as having less stomach
irritation. However, unless the pills are used continuously, the inflammation
comes back.
Recently, I have been introduced to a natural anti-inflammatory
substance discovered in the flower of the Crila plant. Several of our patients
tried Crila with notable improvement to their urinary symptoms. So far we have
not observed any side effects. To investigate Crila’s effectiveness
further, I have petitioned the manufacturer to provide a 3-month supply of
Crila to 15 of our patients at no cost. Patients who have problems with frequent
urination, a strong sense of urinary urgency or have to get up frequently at
night to urinate may want to consider contacting Sabrina in our office about
their eligibility for participating in this clinical trial.
5 comments:
I would like to try Crila for my BPH symptoms.
Saw palmetto, Beta sitosterol, and other herbal remedies don't work.
Please provide dosage recommendations for Crila.
Steve Taylor
Dr. Scholz: the 3 month trial may not be sufficient to determine Crila's effectiveness, if the guidelines of the supplier, Crilahealth.com are followed. According to their web-site, a "load phase" for a minimum of 60-90 days is preferred to achieve "optimal results". The dosage for the period also varies in accordance to bodyweight. For example, a 110 # individual would take 4 pills/day whereas a 300 # individual would take 11 pills a day during the load phase. Then after the load phase only 2 pills a day are required. Hence it appears that the trial be extended to a least 6 months, assuming a load phase is about 75 days, average.
At US$130.00 for 180 capsules, this is not an inexpensive protocol.
I wonder what the side effects would be for cardiac patients.
Has Dr. Scholz evaluated the performance of those patients on the clinical trial? Have they "loaded" up with higher dose the first months as recommended by the supplier and as I inquired about earlier in January? I would be interested if the loading has any affect on the performance since I am contemplating using the supplement, but do not want expend a whole lot of money for little benefit in the "load" phase. Thank you for considering.
Here's my story with CRILA from www.crilahealth.com.
Nocturia In the week before starting CRILA . . .
(2, 3, 3, 2, 3, 5, 4), Average = 3.1 x/night. Maximum = 5 x/night.
Start CRILA on 14/3/2016.
After 6-weeks on CRILA, for week ending 25/4/2016 . . .
(2, 2, 3, 3, 1, 3, 3), Average = 2.4 x/night. Maximum = 3 x/night.
After 9-weeks on CRILA, for week ending 16/5/2016 . . .
(1, 2, 1, 3, 1, 1, 1), Average = 1..4 x/night. Maximum = 3 x/night.
I will continue the "load phase" taking 6 capsules of CRILA per day for another week or so, and then reduce to 2 capsules per day.
Steve in Thailand
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